Introduction: Sildenafil citrate 50 mg is the recommended starting dose for men with erectile dysfunction ED ; however, most men are later titrated to sildenafil mg for improved efficacy.
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Aim: Assess the tolerability and efficacy of sildenafil initiated at the mg dose in men with ED. Results: Improvements in DBPC patient-reported outcomes from baseline were statistically significant for both sildenafil 50 and mg compared with placebo. Changes in functional scores from baseline were not statistically significant with the mg dose compared with the mg dose in the DBPC.
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Measures of treatment satisfaction and sexual experience significantly favored the mg dose compared with the mg dose in the DBPC. There was no increase in adverse events with the higher dose.
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Conclusions: Sildenafil at 50 mg or mg significantly improved erection quality, treatment satisfaction, anxiety levels, and the sexual experience compared with placebo during DBPC. Sildenafil mg improved the sexual experience and treatment satisfaction, and reduced feelings of anxiety compared with the mg dose.
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Trial registration: ClinicalTrials. Abstract Introduction: Sildenafil citrate 50 mg is the recommended starting dose for men with erectile dysfunction ED ; however, most men are later titrated to sildenafil mg for improved efficacy.
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Associated data ClinicalTrials.
